Research

The UI College of Dentistry and Dental Clinics is a global leader in oral science and dental and craniofacial research

Dental Research with a lasting impact

At the forefront of innovation, the College of Dentistry is advancing oral health research with a mission to address both foundational and emerging challenges in dental science. Our research spans a wide range of topics, from improving patient outcomes and developing new technologies to tackling the underlying causes of oral diseases. Each study, whether in the lab or clinic, reflects our commitment to enhancing the quality of life for individuals and communities around the world.

Over the last several years, the UI College of Dentistry has more than doubled its external research funding from the National Institute of Dental and Craniofacial Research (NIDCR), vaulting from 24th in the nation and $2.2M to 13th overall and $4.8M in the latest rankings.

8

major areas of research

# 13

nationally in NIDCR funding

$ 26M +

in funding since 2022

40 %

of DDS students participate in research

Chart depicting the funding sources for COD grants in FY25

Research News

Can arginine toothpaste also improve gum health?

Tuesday, February 10, 2026

Sukirth Ganesan is leading a clinical study examining whether an arginine‑containing toothpaste can influence the subgingival microbiome in patients receiving supportive periodontal care. The six‑month trial will track microbial and clinical changes to determine whether this common dentifrice ingredient can support long‑term periodontal health without increasing disease risk.

Iowa periodontist explores how metabolic health shapes the oral microbiome

Wednesday, February 4, 2026

Sukirth Ganesan received an NIH R01 award to study how improvements in metabolic health influence the oral microbiome. The interdisciplinary research team, led by Ganesan, includes investigators from the College of Dentistry and the Carver College of Medicine, spanning expertise in endocrinology, bariatric surgery, nutrition and dietetics, immunology, biochemistry, and computational biology. His team will track microbial and metabolic changes in the mouth over time to identify early biomarkers that support prevention and improve oral and overall health outcomes.