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Research News 2014

Raymond Kuthy

Dr. Ray Kuthy will serve on the Expert Work Group, which was established by the Oral Health Workforce Center (OHWRC) to serve in an advisory capacity and provide assistance to the OHWRC research team.

12/05/2014

Dr. Raymond Kuthy, Department of Preventive & Community Dentistry, has joined the newly established Expert Work Group, which was established by the Oral Health Workforce Center (OHWRC) to serve in an advisory capacity and provide assistance to the OHWRC research team in strengthening its research products. The Center for Health Workforce Studies at the SUNY Albany School of Public Health was recently awarded a Cooperative Agreement from the federal Health Resources and Services Administration to establish OHWRC.

Members of the Expert Work Group also include Dr. Tom Ricketts, Sheps Center, University of North Carolina, Chapel Hill; Dr. Marko Vujicic from the American Dental Association; Dr. Paul Glassman, University of the Pacific; and Ann Battrell, American Dental Hygiene Association.

Ghadeer Thalji

Dr. Ghadeer Thalji, Department of Prosthodontics, received the Glaxo-Smith-Kline Prosthodontic Innovator Award during the recent annual session of the American College of Prosthodontists.

12/05/2014

Dr. Ghadeer Thalji received the Glaxo-Smith-Kline Prosthodontic Innovator Award during the recent annual session of the American College of Prosthodontists. The award is given to acknowledge those who advance the understanding of prosthodontics-related biological and/or material systems, human behavior, cost and care delivery, as well as economic modeling and quality of life in their investigations.

Kim Brogden

Dr. Kim Brogden receives the Board of Regents Award for Faculty Excellence.

10/08/2014

Dr. Kim A. Brogden, director of Dows Institute for Dental Research and professor of Periodontics with the College of Dentistry, was among almost 30 individuals honored at the University of Iowa’s annual Faculty and Staff Awards Banquet Tuesday, Oct. 7, sponsored by the Office of the Provost and the Office of the Vice President for Human Resources. Dr. Brogden received the Board of Regents Award for Faculty Excellence. The award, given by the Board of Regents, State of Iowa, in cooperation with the Faculty Senate, honors faculty members who have made significant contributions to excellence in public education across the domains of teaching, research, and service.

Dr. Brogden’s research, which focuses on peptides in saliva and their role in oral inflammation and immune response, has drawn acclaim from collaborators and peers around the world and has been funded by the National Institutes of Health and the U.S. Department of Agriculture.

Since 2012 he has served as director of the Dows Institute for Dental Research, and he is highly regarded as an effective administrator. He led the planning for a recent renovation of the College of Dentistry’s research laboratories, which has greatly improved the utility and flexibility of those spaces.

Dr. Brogden teaches a range of pre- and post-doctoral microbiology courses, and his guidance as a mentor has resulted in many students winning awards locally and nationally. He has twice received the College of Dentistry Mentor of the Year award, and in 2012 he received the American Academy of Periodontology’s Educator Award in recognition of outstanding teaching and mentoring.

In welcome remarks, UI President Sally Mason said that during her travels around the state, across the country, and even around the world, she has heard many stories of how a professor or a staff member at the UI changed someone’s life.

“I have heard how an idea in the mind of a young student going to classes on our campus turned into a brilliant career, how gratefulness for how our health care and health sciences have saved someone’s life, and I have heard appreciation for how the university has helped a small business thrive,” Mason said. “Tonight is the night we celebrate how we are able to inspire ideas, save lives, improve our state, and make the world a better place.” 

image of Dr. Levy

Dr. Steven Levy receives a $302,000 NIDCR Grant

09/10/2014

A new $302,000 grant entitled “Secondary Analyses of Adolescent Caries, Including Fluoride, Diet, and Other Factors” has been awarded by the National Institute of Dental and Craniofacial Research (NIDCR) to the University of Iowa College of Dentistry. The two-year award will support detailed secondary data analyses of patterns of dental caries incidence from age 13 to 17 years among children in the Iowa Fluoride Study; support will also include complex analyses of the longitudinal predictors of dental caries incidence that include demographic factors, previous caries experience, fluoride intake and exposures, and dietary intakes and patterns.

The principal investigator is Dr. Steven Levy, Wright-Bush-Shreves Endowed Professor of Research, Preventive and Community Dentistry, and professor, epidemiology, College of Public Health. Co-investigators include Drs. John Warren, and Teresa Marshall, Preventive and Community Dentistry, and Dr. Joseph Cavanaugh, Department of Biostatistics, College of Public Health.

The Iowa Fluoride Study cohort has been followed and studied since their birth through recruitment of the mothers in 1992-95; the young adults are now aged 19-22. Several previous NIDCR grants have supported this unique longitudinal study. The age 17 dental examinations and related questionnaire data collection recently were supported by grants from the Roy J. Carver Charitable Trust and Delta Dental of Iowa Foundation, without whose support this NIDCR grant award would not have been possible. 

Ghadeer Thalji

Dr. Ghadeer Thalji, Department of Prosthodontics, has received an eighteen-month, $63,986 grant from the Osteology Foundation.

08/28/2014

Dr. Ghadeer Thalji, Department of Prosthodontics, has received an eighteen-month, $63,986 grant from the Osteology Foundation. Her research project is "Comparative Assessment of Alternative Macrophage Differentiation in an Early Osseointegration Model in Health Non-Obese Patients vs. Obese Type II Diabetics."

The project's goal will be to evaluate the effects of obese individuals on the modulation of gene transcription related to acquisition of M2 properties in implant adherent cells in an oral implant integration model compared with non-obese, non-diabetic individuals. She also hopes to gain preliminary insight into the osteoinductive nature of adjacent osteoprogenitor cells that may be influenced by the phenotype of the neighboring monocytes.

Co-investigators include Dr. Clark Stanford, Dows and Prosthodontics, and Dr. Lyndon Cooper, University of North Carolina.

Leonardo Marchini

Dr. Leonardo Marchini, Department of Preventive & Community Dentistry, has received a two-year, $166,440 Delta Dental of Iowa Foundation grant.

08/14/2014

Dr. Leonardo Marchini, Department of Preventive & Community Dentistry, has received a two-year, $166,440 Delta Dental of Iowa Foundation grant for his research, "Iowa Nursing Facility Oral Hygiene Intervention: A Pilot Study." His research will evaluate the effectiveness of dental hygienist-delivered oral health interventions in six area Iowa nursing facilities.

Co-investigators will include Drs. Michael Kanellis, Clinic Administration; Jennifer Hartshorn, Howard Cowen, and Daniel Caplan, all Department of Preventive & Community Dentistry; Deborah Dawson, Biostatistics Unit; and David Drake, Dows Research.

Azeez Butali

Dr. Azeez Butali has been selected as a Harold Amos Scholar by the Robert Wood Johnson Foundation.

08/05/2014

Dr. Azeez Butali, Dows Research and Department of Oral Pathology, Radiology and Medicine, has been selected to participate in the Harold Amos Medical Faculty Development Program of The Robert Wood Johnson Foundation. He was one of 10 chosen scholars out of 74 applicants nationwide.

As an Amos Scholar, Dr. Butali will receive an annual stipend up to $75,000 over four years, complemented by a $30,000 annual grant toward his research support.  He will spend at least 70% of his time conducting research with a senior faculty member located at an academic medical center or dental school noted for the training of young faculty and will pursue lines of investigation in his field of interest. His research project, which will be conducted at the UI College of Dentistry, will be “A Genome-wide Association Study for Non-syndromic Clefts in sub-Saharan African Population.” Ms. Tamara Busch, a research assistant in the College of Medicine, will be working with Dr. Azeez.

Dr. Butali's scholarship will begin following completion of the required paperwork.

Dr. Leonardo Marchini

Dr. Leonardo Marchini, assistant professor with the preventive and community dentistry department at the College of Dentistry, received the Colgate-GABA Research Award at the 2014 European College of Gerodontology (ECG) meeting in Böblingen, Germany, June 19 – 21, 2014.

06/26/2014

Dr. Leonardo Marchini, assistant professor with the preventive and community dentistry department at the College of Dentistry, received the Colgate-GABA Research Award at the 2014 European College of Gerodontology (ECG) meeting in Böblingen, Germany, June 19 – 21, 2014, and was elected ECG Counsellor. The ECG - GABA Research Award supports and recognizes research in the field of gerodontology. The prize is awarded annually during the ECG meeting.

The study, entitled “Bone metabolism related gene expression in early phase of residual ridge resorption in human mandibles,” was done at the State University of Sao Paulo (UNESP), Brazil. The researchers’ team included Elis Andrade de Lima Zutin, Leonardo Marchini, Marcia Sampaia Campos, Alecsandro de Moura Silva, Patricia Pimentel de Barros, and Antonio Olavo Cardoso Jorge.

ECG, founded in 1990, is a forum for those sharing an interest in the oral care for the elders, a place for fostering international cooperation on research in gerodontology, and a setting for a European body that addresses questions on oral health, oral health policies and educational aspects for gerodontology. ECG meetings regularly cover not only the “hard core science,” but also a wide range of clinical aspects of dental treatment of the older adults.

In 1999, the ECG held its annual meeting for the first time in conjunction with the American Society for Gerodontology (ASGD) in Montreal, and thus broadened the “European” perspective in the field. With a growing interest in the field of gerodontology, ECG members reach far beyond the European borders.

Dr. Clark Stanford

Dr. Clark Stanford, associate dean for research and professor of prosthodontics at the College of Dentistry, has been named dean of the University of Illinois at Chicago College of Dentistry.

05/30/2014

Dr. Clark Stanford, associate dean for research and professor of prosthodontics at the College of Dentistry, has been named dean of the University of Illinois at Chicago College of Dentistry.

“Illinois will be a better place because Clark is arriving, and Iowa will be a different place because Clark is leaving. While Clark cannot be replaced, he has left a sound legacy that will endure. I will personally miss Clark as a colleague, mentor, and friend, and I look forward to working with him as a fellow Big Ten Dean,” said COD Dean David Johnsen.

A native of Northbrook, Illinois, Stanford arrived at the Iowa City campus as an undergraduate in 1979 and never left. He received a bachelor’s of science degree in 1984, a doctor of dental science degree in 1987, and a certificate in prosthodontics and Ph.D. in cell biology in 1992. He joined Iowa’s faculty that same year.

An accomplished researcher whose work has been funded by the National Institutes of Health, private foundations and industry, Stanford focuses his laboratory studies on osteoblastic gene expression and signaling pathways. He is the author of 18 book chapters, 111 published papers and more than 140 research abstracts.

Stanford currently serves on several national and international committees, including the International Association for Dental Research, the National Institutes of Health, the Academy of Prosthodontics and the Academy of Osseointegration.

Stanford has won 15 teaching awards, including the 2007 State of Iowa Regents Award for Faculty Excellence and the International Association for Dental Research Distinguished Science Award that same year. He also treats patients for complex rehabilitation, with an emphasis in craniofacial anomalies, in an intramural practice at the college.

Congratulations, Dr. Stanford! 

IDF Scholarships

Kaitlin Hoogeveen and Courtney Mann Win IDF Scholarships. The Iowa Dental Foundation (IDF) board of directors approved scholarships to ten students during its May board meeting. 

05/16/2014

The Iowa Dental Foundation (IDF) board of directors approved scholarships to ten students during its May board meeting. Kaitlin Hoogeveen and Courtney Mann, third-year students at the College of Dentistry, each were awarded $5,000 scholarships.

Dr. Chris Barwacz, assistant professor with the Craniofacial Clinical Research Center, is the research mentor for both students. Dr. Barwacz serves as secretary at a University District Dental Society Meeting, where he learned about the scholarship opportunities. Dr. Barwacz encouraged Kaitlin and Courtney to apply.

The application process required submission of students’ CVs, personal statements and letters of reference.

“I was humbled and honored to receive the scholarship. It was a surprise, and I am very grateful to the Iowa Dental Foundation for the award,” said Kaitlin.

Courtney stated: “I am very grateful for the opportunities this scholarship will provide. I appreciate my faculty who wrote letters of recommendation for me and the IDF for their generosity.”

IDF scholarships are available for students wishing to pursue higher education in the field of dentistry. Dental assistants, dental hygienists, dental technicians, and third-year dental students are eligible to apply.

Scholarship applications are due in the IDF offices no later than March 31 of the calendar year. Application are reviewed at the IDF's board meeting the first week of May each year. Scholarship recipients are notified in mid-May.

Congratulations, Kaitlin and Courtney!

COD students

Project SEALED, a University of Iowa initiative, provides oral care for schoolchildren in northeast Allamakee County, Iowa.

05/13/2014

Clean teeth mean happy and healthy children—and possibly a career as a dentist.

That’s the thrust behind a University of Iowa initiative in Allamakee County, Iowa, where third-year UI College of Dentistry students travel four times a year to check schoolchildren’s teeth, offer tips for oral care, and show what it means to be a community dentist.

The program, called Project SEALED, started nearly two years ago as a partnership between the UI and school systems in Postville and Waukon. To date, about 100 dental students have provided care for up to 700 elementary and middle school children in Postville and Waukon.

Dan Caplan, UI dentistry professor and organizer of Project SEALED, says the outreach is much more than helping an underserved population in one of the most ethnically diverse counties in the state. For one, the UI dental students get hands-on experience working in the field, as they think about their careers.

Kaitlin Hoogeveen says the experience reinforces her desire to open a practice in rural, northwest Iowa. “We really love the small town, and the support from the community,” says Hoogeveen, who’s from Sioux Center.

The schoolchildren find out what it’s like to be a dentist, too. To underscore that message, some of them came to Iowa City this month to tour the College of Dentistry and learn more about dentistry.

Dr. Fischer

Dr. Carol Fischer selected to receive TRiO Achiever Award

04/23/2014

Dr. Carol Fischer, postdoctoral research fellow with the Dows Institute for Dental Research at the University of Iowa College of Dentistry, has been selected as the 2014 Oklahoma Division of Student Assistance programs’ TRiO achiever awardee.

During her undergraduate education, Dr. Fischer participated in the McNair Scholars Program, part of a group of federally funded programs collectively known as “TRiO.” The McNair program seeks out first generation undergraduate students, interested in education beyond a bachelor’s degree, to cultivate, encourage, and assist them to attain graduate school status. Participating students become involved in research projects, special classes, seminars, and conferences and are assigned an additional mentor to help them.

As the awardee, Dr. Fischer will present at both state and regional conferences and will serve as the state representative of the TRiO program.

Dr. Fischer acknowledges that although she was aware that the McNair program had followed her accomplishments through graduate school, she was quite surprised when she heard the program was nominating her for this award. She states, “I didn’t even know it existed – and I was very excited to receive this notification!”

Mari Heslinga

Mari Heslinga (D2) Selected for the Paul Ambrose Scholars Program.

04/18/2014

Mari Heslinga, a second-year student with the College of Dentistry, has been accepted into the Paul Ambrose Scholars Program (PASP), part of the Association for Prevention Teaching and Research (APTR).

PASP prepares public health and clinical health professions students to address population health challenges at the national and community level, seeking to meet the current and future health needs of the public. PASP provides mini-grant funds to selected students to implement a Healthy People 2020 Leading Health Indicators project within students’ communities or at their academic institutions.

Since 2002, more than 500 students from over 160 academic institutions have become Paul Ambrose Scholars. The program is named after Paul Ambrose, M.D., M.P.H., a rising star in the medical community who lost his life on September 11, 2001, in the American Airlines flight 77 crash. His commitment to promoting public health and preventing disease was a critical force in the development of The Surgeon General's Call to Action to Prevent and Decrease Overweight and Obesity for which he served as a senior editor. Following his personal vision, PASP supports leadership development for students pursuing careers in preventive medicine and public health.

As a 2014 PASP Scholar, Mari will attend the Student Leadership Symposium in Washington, District of Columbia, from June 20-22, 2014. Mari will be among 40 health professions students from across the country. During the Symposium, scholars will gain a deeper understanding of the complexities and varying attitudes toward public health and learn methods to affect change in their own community. Past Symposium speakers include prominent public health officials such as Surgeons General, Assistant Secretaries for Health and other governmental officials, industry experts, and veteran public health practitioners.

Each student scholar will receive a $200.00 stipend after completing the Symposium activities. The stipend will be used to implement a community-based project addressing one of the Healthy People 2020 Leading Health Indicators (LHIs). Student scholars have up to one year to complete their projects and request reimbursement for their project-related expenses (up to $350.00).

Mari is very excited to become part of the program, and is thankful to her mentor, Dr. Steve Levy,Preventive & Community Dentistry,for his support and his time. Mari says, "This is going to be a great project to work on."

Satheesh Elangovan

Dr. Satheesh Elangovan, Department of Periodontics, has received a one-year Academy of Oseointegration grant for $14,500.

03/31/2014

Dr. Satheesh Elangovan, Department of Periodontics, has received a one-year Academy of Osseointegration grant for $14,500. The grant will be used for his research project, "An in vitro Assessment of a Tissue Engineering Titanium Surface for Enhanced Peri-Implant Healing."

Dr. Veerasathpurush Allareddy, Department of Orthodontics; Dr. Liu Hong, Department of Prosthodontics; and Dr. Aliasger Salem, College of Pharmacy, will be co-investigators on the grant. Dr. Georgia Johnson, head of the Department of Periodontics, and Clark Stanford, associate dean for research, will be consultants.

Sreedevi Srinivasan

Dr. Sreedevi Srinivasan, Department of Orthodontics, has received an award from the AAOF Foundation.

03/31/2014

Dr. Sreedevi Srinivasan, Department of Orthodontics, has received a one-year $15,000 Orthodontic Faculty Development Fellowship Award from the American Association of Orthodontists Foundation (AAOF).

The award will support her research project, "Assessment of Jaw Growth Using Biomarkers in Saliva and Gingival Crevicular Fluid: A Pilot Study." Her co-investigators will include Dr. Brad Amendt, UI College of Medicine, and Dr. Deborah Dawson, Biostatistics Unit. Dr. Andrew Norris and Dr. Jeff Murray, both College of Medicine, will be consultants. Dr. Thomas Southard, Department of Orthodontics chair, will be an advisor.

Ben Nashleanas

A research article published by Ben Nashleanas (D3) is currently the Editor's Choice for the online journal BMC Oral Health.

03/31/2014

A research article published by Ben Nashleanas (D3) has been the Editor's Choice for the online journal BMC Oral Health.

Ben's article, "Career influences among final year dental students who plan to enter private practice," can be found at http://www.biomedcentral.com/bmcoralhealth.

Co-authors includes Drs. Susan McKernan, Raymond Kuthy, and Fang Qian, Department ofl Preventive & Community Dentistry. Drs. Kuthy and McKernan are Ben's mentors.

Carol Fischer

Dr. Carol Fischer has been selected as the 2014 Oklahoma Division of Student Assistance Programs' TRiO achiever awardee.

03/04/2014

Dr. Carol Fischer, postdoctoral research fellow, Dows, has been selected as the 2014 Oklahoma Division of Student Assistance programs' TRiO achiever awardee.

During her undergraduate education, Dr. Fischer participated in the McNair Scholar's Program, which is part of a group of federally funded programs collectively known as "TRiO." The McNair program seeks out first general undergraduate students who are interested in education beyond a bachelor's degree to cultivate, encourage, and help them attain a graduate school status. Participating students become involved in research projects, special classes, seminars, and conferences, and are assigned an additional mentor to help them.

As the awardee, Dr. Fischer will present at both state and regional conferences and will also serve as the state representative of the TRiO program.

Azeez Butali

Dr. Azeez Butali, Department of Oral Pathology, Radiology, and Medicine, and Dows, has received a three-year NIH grant.

03/04/2014

Dr. Azeez Butali, Department of Oral Pathology, Radiology and Medicine, and Dows, has received a three-year grant from the U.S. Deparment of Health & Human Services, National Institutes of Health. The first year's amount is $224,000.

The goal of his project, "Genetic Studies of Nonsyndromic Clefts in Populations of African Descent," is to understand the complex genetic etiology of orofacial clefts (OFC) by determining the genetic variations that contribute to OFC in homogenous African populations and relate these findings to prevention and clinical management of the disease. The study will also focus on genome-wide association studies (common variant association studies (CVAS) and rare variant association studies (RVAS) of non-syndromic clefts using homogenous samples from Africa.

Dr. William Giannobile

Dr. William Giannobile was the keynote speaker for 61st Meeting of Iowa Section of AADR.

02/21/2014

The 61st Annual Meeting of the Iowa Section of the American Association for Dental Research (AADR) was held at the College of Dentistry on February 11, 2014. There were 88 presenters (faculty, students, and staff) for this year's Local Research Day. The awards banquet was held that evening at the Coralville Holiday Inn.

Dr. William Giannobile, Najjar Endowed Professor of Dentistry & Biomedical Engineering at the University of Michigan School of Dentistry and College of engineering, was the keynote speaker. His presentation was "Oral and Periodontal Regenerative Medicine: Prospects for the Future."

Dr. Giannobile has published and lectured about periodontal regenerative medicine and tissue engineering and has also authored several textbooks in clinical research and periodontal research methodologies. He is editor-in-chief of the Journal of Dental Research and a consultant to the Food and Drug Administration, the National Institutes of Health, and several biotechnology companies focused on regenerative medicine. Dr. Giannobile is a diplomate of the American Board of periodontology and maintains a private practice in Ann Arbor, Michigan, that is limited to periodontics and implantology.

Ghadeer Thalji

Dr. Ghadeer Thalji receives an ITI Foundation Grant.

02/21/2014

Dr. Ghadeer Thalji, Department of Prosthodontics, has received a one-year, $48,000 International Team for Implantology (ITI) Foundation Grant.

Dr. Thalji will conduct a cross-sectional observational study, where she will place two SLAactive Standard Plus Straumann implants (4.1x6 mm) in edentulous sites of 12 systematicallly healthy, non-obese human subjects and 12 obese type 2 diabetics. One implant will subsequently be removed after 3 and 7 days. Total RNA will be isolated from cells adherent to retrieved implants. Expression of M2 markers and key osteoblastic transcription factors (RUNX2 and OSX) will be analyzed by real-time quantitative PCR method.

Co-investigators include Dr. Clark Stanford, Department of Prosthodontics and Dows, and Dr. Deborah Dawson, director of the Biostatistics Unit.

Daniel Caplan

Dr. Daniel Caplan receives a Delta Dental of Iowa Foundation Grant.

02/21/2014

Dr. Daniel Caplan, head of the Department of Preventive & Community Dentistry, has received a one-year, $25,000 grant from the Delta Dental of Iowa Foundation. The grant money will be used for his project, "Association between Dental Treatment and Time-to-Death among Nursing Home Residents of Eastern Iowa." The goal of the project is to describe the types and timing of dental treatment provided to 586 nursing home residents in four Eastern Iowa counties and to evaluate whether that treatment is related to time-to-death in that population.

Dr. Tariq Ghazal, a graduate student in the oral sciences PhD program, is currently working with Dr. Caplan on the data analysis.

Isabelle Denry

Dr. Isabelle Denry, Department of Prosthodontics and Dows, has been appointed to the editorial board of Journal of Dental Research (JDR).

02/21/2014

Dr. Isabelle Denry, Department of Prosthodontics and Dows, has been appointed to the editorial board of Journal of Dental Research (JDR).

Dr. Deborah Dawson, director of the Biostatistics Unit, is also currently an editorial board member of JDR.

Dr. William V. Giannobile, University of Michigan, is currently the editor-in-chief of JDR. He was the keynote speaker for the 61st Annual Meeting of the Iowa Section of the American Association for Dental Research, which was held February 11.