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Aspire to the highest standards of excellence in research, education and service


Support and enhance College of Dentistry’s core values, goals and strategies through collaborative research and innovations in quantitative dental sciences


The purpose of The University of Iowa College of Dentistry Division of Biostatistics and Computational Biology(BCB) is to provide state-of-the-art and cost-effective biostatistics and bioinformatics support for all the research projects conducted at the College through a spectrum of collaborations. The format of these collaborations ranges from long term grant and protocol support, project oriented assistance, to ongoing consultations and data analyses. These collaborations include:

  • To conduct preliminary data analysis and assist in research hypothesis formulating.
  • To review background rationale and to provide statistical design and analysis plans required to address the specific aims of clinical protocols, translational and basic science research projects.
  • To provide proper analysis and interpretations of data collected from bioassays, drug screening, animal models, clinical investigations, and population-based studies.
  • To assist in manuscript preparation and to review scientific submissions.
  • To critically review and advise on clinical protocols to be conducted at College of Dentistry.
  • To provide database development and computer programming services and to assure data quality control.
  • To provide general statistics and bioinformatics consultations to all College of Dentistry investigators.
  • To provide special education and training opportunities (lectures and lab meeting discussions) in biostatistics and bioinformatics to students, residents, fellows and junior faculty investigators.
  • To conduct quantitative methodological research that is directly applicable in dental science.

Division of Biostatistics and Computational Biology provides the necessary infrastructure to facilitate collaboration between investigators and biostatisticians/bioinformaticians from the planning stage of a project through its execution, analysis, interpretation of results, and scientific submissions.


The main goal of BCB is to ensure appropriate quantitative support for biomedical research at the College of Dentistry through a recognized and accessible central resource.  BCB will support all clinical and population-based research as well as in vitro and animal research. However the highest priority will be given to the peer-reviewed funded research, clinical protocol development, and statistical review service to IRB and DSMC. The order of priority among research projects is as follows:

(1) Peer-reviewed funded research projects and clinical trials (funding should include BCB support);

(2) Non-peer-reviewed funded research projects and clinical trials (funding should include BCB support);

(3) Research proposals to be submitted for external funding (there should be a budget for BCB support);

(4) Investigator initiated clinical trials without external funding;

(5) Other research projects without external funding.


Division of Biostatistics and Computational Biology is directed by Dr. Xian Jin Xie.

How to Access Statistical Assistance
Graduate Committee Service