Galen B. Schneider
Galen B. Schneider, D.D.S., Ph.D, FACP
Executive Associate Dean
Professor, Department of Prosthodontics
Expertise:
Removable, fixed and implant-supported prosthodontics
Education:
DDS, University of Iowa, 1991
PhD, University of North Carolina, 1996
Certificate, Prosthodontics, University of North Carolina, 1996
Diplomate, American Board of Prosthodontics, 2008
Fellow, American College of Prosthodontists, 2008
Fellow, American Dental Education Association Leadership Institute, 2010
Fellow, American College of Dentists, 2016
To Make An Appointment:
319-335-7275
Brief Professional Resume:
Dr. Schneider joined the University of Iowa College of Dentistry in 1999. He served as Department of Prosthodontics chair from 2006-2011. He is currently executive associate dean and a professor in the Department of Prosthodontics, with a joint appointment in the UI Institute for Dental Research.
Clinical Activities:
Dr. Schneider is a board-certified prosthodontist and is actively involved in patient treatment within the Department of Prosthodontics' intramural practice.
Research Activities:
Dr. Schneider's research focuses on bone cell biology as it related to implant osseointegration and bone tissue engineering.
Publications:
1. (Book Chapter): Stanford C, Schneider GB, Perinpanayagam H, Keller J, Midura R. Biomedical Implant Surface Topography and its Effects on Osteoblast Differentiation, in vitro. Chapter 8. Bio-implant Interface: Improving Biomaterials and Tissue Reactions. 2003:139-162.
2. Schneider GB, Cunningham-Ford MA, Johnsen DC, Eckert M, Mulder M. Outcome mapping: a method for dental schools to coordinate learning and assessment based on desired characteristics of a graduate. J Dent Educ 2014;78(9):1268-1278. PubMed PMID: 25179923.
3. Hoyle D, Ryan P, Hand JS, Damiano PC, Schneider GB. Retaining new dentists in Iowa: a role for dental schools in facilitating graduates' connections to practice opportunities in underserved areas. J Dent Educ 2014;78(4):512-519. PubMed PMID: 24706680.
4. Marshall S, Low L, Holton N, Franciscus R, Frazier M, Qian F, Mann K, Schneider GB, Scott J, Southard T. Chin development as a result of differential jaw growth. Am J Orthod Dentofacial Orthop 2011; (139):456-464. PubMed PMID: 21457856.
5. Cashman P, Schneider R, Schneider GB. In vitro analysis of post fatigue reverse torque values at the abutment/implant interface for a unitarian abutment design. J Prosthodont 2011;20(7):503-509. PubMed PMID:21880095.
6. Hong L, Krishnamachari Y, Seabold D, Joshi V, Schneider GB, Salem A. Intracellular release of 17-Beta estradiol from cationic polyamidoamine dendrimer surface modified poly-lactic-co-glycoloic acid microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Engineering 2011;17(3):319-325. PubMed PMID: 20883116.
7: Schneider GB, Synan WJ. Use of a single implant to retain a mandibular complete overdenture on the compromised atrophic alveolar ridge: a case report. Spec Care Dentist. 2011 Jul-Aug;31(4):138-42. doi: 10.1111/j.1754-4505.2011.00196.x. PubMed PMID: 21729123.
8: Schneider GB, Zaharias R, Seabold D, Stanford C. Integrin-associated tyrosine kinase FAK affects Cbfa1 expression. J Orthop Res. 2011 Sep;29(9):1443-7. doi: 10.1002/jor.21382. Epub 2011 Mar 15. PubMed PMID: 21412826.
9: Ko J, Zaharias RS, Seabold DA, Lafoon JE, Schneider GB. Analysis of the attachment and differentiation of three-dimensional rotary wall vessel cultured human preosteoblasts on dental implant surfaces. Int J Oral Maxillofac Implants. 2010 Jul-Aug;25(4):722-8. PubMed PMID: 20657867.
10: Boehrs J, Zaharias RS, Laffoon J, Ko YJ, Schneider GB. Three-dimensional culture environments enhance osteoblast differentiation. J Prosthodont. 2008 Oct;17(7):517-21. doi: 10.1111/j.1532-849X.2008.00330.x. Epub 2008 Jun 20. PubMed PMID: 18573152.
11: Baman NK, Schneider GB, Terry TL, Zaharias R, Salem AK. Spatial control over cell attachment by partial solvent entrapment of poly lysine in microfluidic channels. Int J Nanomedicine. 2006;1(2):213-7. PubMed PMID: 17722538; PubMed Central PMCID: PMC2426782.
12: Ko J, Zaharias RS, Seabold DA, Lafoon J, Schneider GB. Osteoblast differentiation is enhanced in rotary cell culture simulated microgravity environments. J Prosthodont. 2007 Nov-Dec;16(6):431-8. Epub 2007 Jun 9. PubMed PMID: 17559538.
13: Cho P, Schneider GB, Kellogg B, Zaharias R, Keller JC. Effect of glucocorticoid-induced osteoporotic-like conditions on osteoblast cell attachment to implant surface microtopographies. Implant Dent. 2006 Dec;15(4):377-85. PubMed PMID: 17172956.
14. Stanford C, Schneider GB, Masaki C, Zaharias R, Seabold D, Eckdahl J, Di Paola J. Effects of fluoride modified titanium dioxide grit blasted implant surfaces on platelet activation and osteoblast differentiation. Applied Osseointegration Res 2006;5:24-30.
15. Isa Z, Schneider GB, Zaharias R, Seabold D, Stanford C. Effects of fluoride modified titanium surfaces on osteoblast proliferation and gene expression. Int J Oral Maxillofac Implants 2006;21:203-211.
16: Darbro BW, Schneider GB, Klingelhutz AJ. Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes. J Invest Dermatol. 2005 Sep;125(3):499-509. PubMed PMID: 16117791; PubMed Central PMCID: PMC2020850.
17. Du C, Schneider GB, Zaharias R, Abbott C, Seabold D, Stanford C, Oldak J. Apatite/Amelogenin coating on titanium promotes osteogenic gene expression. J Dent Res 2005;84(11):1070-1074. PubMed PMID: 16246944.
18. Masaki C, Schneider GB, Zaharias R, Seabold D, Stanford C. Effects of implant surface microtopography on osteoblast gene expression. Clinical Oral Implant Res 2005;16:650-656. PubMed PMID: 16307571.
19. Hess A, Postovit L, Margaryan N, Seftor E, Schneider GB, Schaller M, Seftor R, Nickoloff B, Hendrix M. Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res 2005;65(21):9851-9860. PubMed PMID: 16267008.
20. Kremenak N, Bayne S, McCracken M, Schneider GB. Writing the basic science research report. J Prosthodont 2005;14(2):150-151.
21: Facer SR, Zaharias RS, Andracki ME, Lafoon J, Hunter SK, Schneider GB. Rotary culture enhances pre-osteoblast aggregation and mineralization. J Dent Res. 2005 Jun;84(6):542-7. PubMed PMID: 15914592.
22: Keller JC, Stewart M, Roehm M, Schneider GB. Osteoporosis-like bone conditions affect osseointegration of implants. Int J Oral Maxillofac Implants. 2004 Sep-Oct;19(5):687-94. PubMed PMID: 15508984.
23: Gasparoni A, Fonzi L, Schneider GB, Wertz PW, Johnson GK, Squier CA. Comparison of differentiation markers between normal and two squamous cell carcinoma cell lines in culture. Arch Oral Biol. 2004 Aug;49(8):653-64. PubMed PMID: 15196983.
24: Stanford CM, Schneider GB. Functional behaviour of bone around dental implants. Gerodontology. 2004 Jun;21(2):71-7. PubMed PMID: 15185986.
25. Perinpanayagam H, Schneider GB, Holtman K, Zaharias R, Stanford C. Altered Cbfa1 expression and biomineralization in an osteosarcoma cell line. J Orthopaedic Res 2004;22:404-410. PubMed PMID: 15013103.
26. Sood A, Coffin J, Schneider GB, Fletcher M, DeYoung B, Gruman L, Gershenson D, Schaller M, Hendrix M. Biological significance of FAK in ovarian cancer: role in migration and invasion. Am J of Pathol 2004;165(4):1087-1095. PubMed PMID: 15466376.
27: Schneider GB, Zaharias R, Seabold D, Keller J, Stanford C. Differentiation of preosteoblasts is affected by implant surface microtopographies. J Biomed Mater Res A. 2004 Jun 1;69(3):462-8. PubMed PMID: 15127393.
28. Casa M, Johnson G, Schneider GB, Gasparoni A, Squier C, Fonzi L. Cell membrane molecules in oral cancer. Dent Cadmos 2004;72:55-65.
29: Cho P, Schneider GB, Krizan K, Keller JC. Examination of the bone-implant interface in experimentally induced osteoporotic bone. Implant Dent. 2004 Mar;13(1):79-87. PubMed PMID: 15017309.
30: Schneider GB, English A, Abraham M, Zaharias R, Stanford C, Keller J. The effect of hydrogel charge density on cell attachment. Biomaterials. 2004 Jul;25(15):3023-8. PubMed PMID: 14967535.
31: Fakhry A, Schneider GB, Zaharias R, Senel S. Chitosan supports the initial attachment and spreading of osteoblasts preferentially over fibroblasts. Biomaterials. 2004 May;25(11):2075-9. PubMed PMID: 14741622.
32: Keller JC, Schneider GB, Stanford CM, Kellogg B. Effects of implant microtopography on osteoblast cell attachment. Implant Dent. 2003;12(2):175-81. PubMed PMID: 12861887.
33: Schneider GB, Perinpanayagam H, Clegg M, Zaharias R, Seabold D, Keller J, Stanford C. Implant surface roughness affects osteoblast gene expression. J Dent Res. 2003 May;82(5):372-6. PubMed PMID: 12709504.
34: Schneider GB, Kurago Z, Zaharias R, Gruman LM, Schaller MD, Hendrix MJ. Elevated focal adhesion kinase expression facilitates oral tumor cell invasion. Cancer. 2002 Dec 15;95(12):2508-15. PubMed PMID: 12467064.
35: Gasparoni A, Chaves A, Fonzi L, Johnson GK, Schneider GB, Squier CA. Subcellular localization of beta-catenin in malignant cell lines and squamous cell carcinomas of the oral cavity. J Oral Pathol Med. 2002 Aug;31(7):385-94. PubMed PMID: 12165056.
36: Odero-Marah VA, Khalkhali-Ellis Z, Schneider GB, Seftor EA, Seftor RE, Koland JG, Hendrix MJ. Tyrosine phosphorylation of maspin in normal mammary epithelia and breast cancer cells. Biochem Biophys Res Commun. 2002 Jul 26;295(4):800-5. PubMed PMID: 12127964.
37. Schneider GB. Collaborations must be developed. J Prosthod 2002;11:2-3. PubMed PMID: 11958171.
38: Davies KR, Schneider GB, Southard TE, Hillis SL, Wertz PW, Finkelstein M, Hogan MM. Deciduous canine and permanent lateral incisor differential root resorption. Am J Orthod Dentofacial Orthop. 2001 Oct;120(4):339-47. PubMed PMID: 11606957.
39. Peripanayagam H, Zaharias R, Stanford C, Brand R, Keller J, Schneider GB. Early cell adhesion events differ between osteoporotic and non-osteoporotic osteoblasts. J Orthopaedic Res 2001;19(6):993-1000. PubMed PMID: 11781027.
40: Schneider GB, Zaharias R, Stanford C. Osteoblast integrin adhesion and signaling regulate mineralization. J Dent Res. 2001 Jun;80(6):1540-4. PubMed PMID: 11499509.
41: Hess AR, Seftor EA, Gardner LM, Carles-Kinch K, Schneider GB, Seftor RE, Kinch MS, Hendrix MJ. Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2). Cancer Res. 2001 Apr 15;61(8):3250-5. PubMed PMID: 11309274.
42. Oldak J, Wen H, Schneider GB, Stanford C. Tissue engineering strategies for the future generation of dental implants. Periodontology 2000 2006;41:157-176. PubMed PMID: 16686932.
43. Schneider GB, Whitson SW, Cooper LF. Restricted and coordinated expression of beta3-integrin and bone sialoprotein during cultured osteoblast differentiation. Bone 1999;24(4):321-7. PubMed PMID: 10221544.
44. Shen Y, Schneider GB, Cloutier JF, Veillette A, Schaller M. Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin. J Biol Chem 1998;273:6474-6481. PubMed PMID: 9497381.
45. Schneider GB, Hamano H, Cooper LF. In vivo evaluation of hsp27 as an inhibitor of actin polymerization: hsp27 limits actin stress fiber and focal adhesion formation after heat shock. J Cell Physiol 1998;177(4):575-84. PubMed PMID: 10092210.
46. Schneider GB, Gilmore AP, Lohse DL, Romer LH, Burridge K. Microinjection of protein tyrosine phosphatases into fibroblasts disrupts focal adhesions and stress fibers. Cell Adhe Commun 1998;5(3):207-19. PubMed PMID: 9686318.
47. Schneider GB, Simmons K, Nason R, Felton D. Occlusal rehabilitation using implants for orthodontic anchorage. J Prosthod 1998;7:232-236. PubMed PMID: 10196843.
48. Uoshima M, Yan YZ, Schneider GB, Aukhil I. The alternatively spliced domains ElllB and ElllA of human fibronectin affect cell adhesion and spreading. J Cell Sci 1997;110:2271-2280. PubMed PMID: 9378776.
49. Pavalko FM, Schneider GB, Burridge K, Lim SS. Immunodetection of alpha-actinin in focal adhesions is limited by antibody inaccessibility. Exp Cell Res 1995;217:534-540. PubMed PMID: 7698254.
50. Schneider GB, Burridge K. Formation of focal adhesions by osteoblasts adhering to different substrata. Exp Cell Res 1994;214:264-269. PubMed PMID: 7521844.
PubMed Publications:
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National or International Professional Appointments and Activities:
Dr. Schneider is a member of the American College of Prosthodontists, the American and International Associations for Dental Research, the American Dental Education Association, and the American Dental Association. He currently serves as a basic science research editor for Journal of Prosthodontics. He is an ad hoc reviewer of articles for the International Journal of Oral and Maxillofacial Implants and Journal of Dental Research; Prosthodontics; Oral and Maxillofacial Implants; Clinical Orthopedics; Biomaterials; Oral Rehabilitation; Nanomedicine; Proceedings of the National Academy of Sciences; Stem Cells and Development; Clinical Oral Implants; Journal of Dental Education; Tissue Engineering; Special Care Dentistry; and Clinical Cancer Research. He has served, or is serving, on committees for the International and American Associations for Dental Research, the American College of Prosthodontists, the International Congress of Oral Implantologists, and the National Institutes of Health.
