Dr. Hong joined the University of Iowa College of Dentistry in 2009. He is an associate professor in the Dows Institute for Dental Research and also in the Department of Prosthodontics. Prior to coming to Iowa, Dr. Hong was an assistant professor in the Department of Orthodontics at the University of Illinois at Chicago and also director of the Stem Cells and Craniofacial Tissue Engineering Lab.
Adult stem cell-based craniofacial tissue engineering, including stem cell biology, in vitro and in vivo bone, cartilage and adipose regeneration, MR monitoring of engineered tissues.
Hong L, Wei N, Joshi V, Yu Y, Kim N, Krishnamachari Y, Zhang Q, Salem A. Effects of glucocorticoid receptor siRNA delivered by poly lactic-co-glycolic acid microparticles on proliferation and differentiation capabilities of human mesenchymal stromal cells. Tissue Eng Part A. 2012 18:775-84.
Yu Y, Wei N, Stanford C, Schmidt T, Hong L. In vitro effects of RU486 on proliferation and differentiation capabilities of human bone marrow mesenchymal stromal cells. Steroids. 2012 77:132-7.
Li W, Hong L, Hu L, Magin RL. Magnetization transfer imaging provides a quantitative measure of chondrogenic differentiation and tissue development. Tissue Eng Part C Methods. 2010 Dec;16(6):1407-15.
Hong L, Zhang G, Sultana H, Yu Y, Wei Z. The effects of 17-β estradiol on enhancing proliferation of human bone marrow mesenchymal stromal cells in vitro. Stem Cells Dev. 2011 May;20(5):925-31.
Hong L, Krishnamachari Y, Seabold D, Joshi V, Schneider G, Salem AK. Intracellular release of 17-β estradiol from cationicpolyamidoamine dendrimer surface-modified poly (lactic-co-glycolic acid) microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Eng Part C Methods. 2011 Mar;17(3):319-25.
Li W, Hong L, Hu L, Magin RL. Magnetization transfer imaging provides a quantitative measure of chondrogenic differentiation and tissue development. Tissue Eng Part C Methods. 2010 May 10 [epub ahead of print].
Hong L, Sultana H, Paulius K, Zhang G. Steroid regulation of proliferation and osteogenic differentiation of bone marrow stromal cells: a gender difference. J Steroid Biochem Mol Biol. 2009 Apr;114(3-5):180-5.
Moioli EK, Hong L, Mao JJ. Inhibition of osteogenic differentiation of human mesenchymal stem cells. Wound Repair Regen. 2007;15(3):413-21.
Hong L, Colpan A, Peptan I, Daw J, George A, Evans C. 17β-estrodial enhances osteogenic and adipogenic differentiation potentials of human adipose-derived stromal cells. Tissue Eng. 2007;13(6):1197-1203.
Hong L, Peptan IA, Colpan A, Daw JL. Adipose tissue engineering by human adipose-derived stromal cells. Cells, Tissues, Organs. 2006;183(3):133-140.
Peptan I, Hong L, Evans C. Multiple differentiation potentials of neonatal dura mater-derived cells. Neurosurgery. 2007;60(2):346-52.
Hong L, Colpan A, Peptan I. Modulations of 17-β estradiol on osteogenic and adipogenic differentiations of human mesenchymal stem cells. Tissue Eng. 2007;12(10):2747-2753.
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Dr. Hong is a member of the Tissue Engineering Society International, the International Association for Dental Research, and the Orthopedic Research Society.