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CCRC Research

Completed Studies

Study Objective Type Statussort descending

PGW12

To evaluate the demineralization and remineralization effects of three experimental fluorides containing dentifrices on enamel and root surface lesions relative to a positive control dentifrice.

Preventative Studies

Closed to recruitment

AST1

A randomized clinical trial examining changes in implant stability upon three different loading regimens during the first 16 weeks following implant placement.

Implant Studies

Closed to recruitment

IVS2

A research study to evaluate the perceived incidence of post-operative sensitivity when a full coverage all ceramic crown is fabricated in the posterior part of the mouth.

Restorative Studies

Closed to recruitment

3M

A partially randomized study to evaluate the demineralization and remineralization effects of 2 experimental fluoride containing dentifrices on enamel and root surface lesions relative to a control dentifrice.

Restorative Studies

Closed to recruitment

Bond Force

A randomized clinical trial to determine and compare the clinical effectiveness and durability of two commercially available adhesive/resin-based restorative systems placed in non-carious class V lesions.

Restorative Studies

Closed to recruitment

IVS3

A clinical trial to evaluate the esthetic and functional outcomes of anterior restorations done with the new Ivoclar composite system.

Restorative Studies

Closed to recruitment

Obesity and Periodontal Inflammation

A cross-sectional study to evaluate obesity as a potential risk factor for inflammation in peri-implant tissues.

Periodontal Studies

Closed to recruitment

ADA Chewing Gum Study

The purpose of this research study is to determine if there is any difference in salivary flow rates and plaque pH changes as a result of chewing three different sugar free chewing gums.  Subjects will use the three test chewing gums at approximately the same time each day.

Preventative Studies

Closed to recruitment

HK1

A randomized clinical trial to evaluate esthetic and functional outcomes of anterior teeth restored with Heraeus Kulzer Diamond compared to a similar market leader composite.

Restorative Studies

Closed to recruitment

TMD

A randomized study to assess the feasibility of conducting a full-scale randomized clinical trial to evaluate the effectiveness of the chiropractic Activator protocol for patients with chronic myofascial TMD.

Craniofacial Studies

Complete

PGW11

A partially randomized study to evaluate the demineralization and remineralization effects of three experimental fluoride containing dentifrices on enamel and root surface lesions relative to a positive control dentifrice.

Restorative Studies

Complete

TvZ Cytokine Study

A comparative study to evaluate the pro-inflammatory levels of key cytokines around implants restored with both titanium and zirconium abutments.

NA

Complete

Posterior Jaw Study

A randomized clinical trial to longitudinally evaluate changes in bone stiffness around dental implants placed in the posterior maxilla.

Implant Studies

Complete

Ongoing Studies

Study Objective Type Statussort descending

Caudry

Esthetic evaluation and clinical efficacy of two piece 3 mm implants in areas of limited space

Implant Studies

Closed to Recruitment

PLUS1

A randomized clinical trial assessing implant stability, marginal bone levels, and long-term implant survival between the Astra Tech OsseoSpeed TX and OsseoSpeed Plus implant systems.

Implant Studies

Closed to recruitment

SCOOP

A randomized clinical trial comparing marginal bone level alterations between 6mm and 11 mm Astra Tech OsseoSpeed implants in posterior jaws.

Implant Studies

Closed to recruitment

PROOF

A randomized clinical trial comparing the buccal soft tissue changes and marginal bone levels occurring around single-tooth implants in the maxilla using three different implant-abutment interface designs.

Implant Studies

Closed to recruitment

Current Studies

Study Objective Type Statussort descending

Salivary Lipids

The purpose of this research is to determine if there are any differences in lipid content and composition in saliva from people with healthy gums compared to people with gum disease.   After giving informed consent, subjects would provide their age, undergo an oral examination by a dentist and spit into a tube for 15 minutes.  The entire process would take about 40 minutes.  Compensation is available.

Preventative Studies

Currently Recruiting

Osteogenics1

The purpose of this study is to clinically and radiographically assess whether the use of a ridge preservation technique significantly minimizes alveolar ridge resorption following tooth extraction.

Periodontal Studies

Currently Recruiting

Atlantis1

A two-arm, parallel group, randomized controlled clinical trial on adult human subjects receiving divergent or concave Atlantis™ abutments to assess peri-implant mucosa changes from prosthesis delivery to 1 year.

  • (Primary) Compare the influence of experimental concavities in the subgingival transition zone of Atlantis™ abutments on peri-implant mucosal dynamics from final restoration delivery to one year, as compared to current Atlantis™ abutments with linear divergent transition profiles.  
  • (Secondary) Quantify the horizontal soft tissue thickness changes around concave and divergent abutment transition profiles from final restoration delivery to one year.  
  • (Secondary) Evaluate changes in peri-implant health indicators, such as Gingival Index (GI), Probing Pocket Depth (PPD), and Bleeding on Probing (BOP).

Implant Studies

Currently recruiting

Short Implant Study

This study aims to determine the effect of obesity in type II diabetics on bone forming cells in healthy non-obese and obese type II diabetic individuals. 

We are recruiting 48 individuals: 24 healthy, non-obese and 24 obese, type II diabetics. Subjects will have two ‘short-implants’ surgically placed and systemically removed and replaced with functional implants over the course of a week.

Implant Studies

Currently recruiting

Jaw Growth & Biomarkers Study

This study aims to identify and establish the levels of growth-associated specific proteins, genes and micro-ribonucleic acids in gingival crevicular fluid and whole saliva in a growing and non-growing human sample population.

Craniofacial Studies

Currently recruiting

Genetics’ Role in the Growth of the Craniofacial Complex

To identify how different facial types develop and how genes modify facial growth and teeth development in order to find a way to improve orthodontic and surgical treatment.

Craniofacial Studies

Recruitment by referral only